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Phentermine (
Systematic (IUPAC) name
2-methyl-1-phenylpropan-2-amine and 2-methyl-amphetamine
CAS number 122-09-8
ATC code A08AA01 C01CA11
PubChem 4771
DrugBank APRD00093
ChemSpider 4607
Chemical data
Formula C10H15N
Mol. mass 149.233 g/mol
Pharmacokinetic data
Bioavailability Peak plasma levels occur within 1 to 4.5 hours. Absorption is usually complete by 4 to 6 hours
Protein binding Approximately 96.3%
Metabolism hepatic
Half life 16 to 31 hours
Excretion Urinary elimination
Therapeutic considerations
Pregnancy cat. C(US)

Legal status Schedule IV(US)

Routes Oral, Insufflation, Intravenous
Phentermine (, a contraction for "phenyl-tertiary-butylamine", is an appetite suppressant of the amphetamine and phenethylamine class.

It is approved as an appetite suppressant to help reduce weight in obese patients when used short-term and combined with exercise, diet, and behavioral modification. It is typically prescribed for individuals who are at increased medical risk because of their weight and works by helping to release certain chemicals in the brain that control appetite.

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